New BioResolve SCX mAb Columns and Consumables Simplify and Improve mAb Characterization and Monitoring through Holistic Approach
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The new Waters BioResolve SCX mAb Columns with Vanguard™ FIT Cartridge technology, together with a suite of complementary consumables, simplify and improve the characterization and monitoring of monoclonal antibody (mAb) therapeutics. (Photo: Business Wire)
“With the introduction of these product offerings, we’re taking a
holistic approach to mAb analysis and moving it a significant step
forward. Scientists now have a complete set of tools for mAb charge
variant analyses that will give them a more complete and detailed
picture of their mAbs and the relationship between mAb structure and
their function,” said Dr.
BioResolve SCX mAb Columns contain an innovative strong-cation exchanger based on a novel polymeric composition, hydrophilic coating and multi-component surface chemistry all synthesized at Waters chemistry manufacturing facility. The base material consists of three-micron non-porous particles for optimal diffusion kinetics, high pressure capability and compatibility with HPLC, UHPLC and UPLC™ methods.
The columns are also available with a first–of-its-kind Vanguard Fully
When used with Waters liquid chromatography systems equipped with Auto•Blend™ PLUS technology, scientists can take advantage of pre-configured Empower™ software methods and automatically blend up to four solvents in any combination or proportion and program in pH and ionic strength. This significantly reduces human error and eliminates the task of preparing buffered mobile phases manually. Waters has also specifically formulated new BioResolve SCX pH buffer concentrates with recommended gradient separation conditions for those scientists looking for a “turnkey” solution for mAb charge variant analyses.
The introduction of the new BioResolve SCX mAb Columns and consumables, along with the recent introduction of the Waters BioAccord™ System, reinforce Waters commitment to innovation and to addressing the evolving needs of the biopharmaceutical industry.
Waters BioResolve SCX mAb Columns and consumables are now available worldwide.
For more information on the Waters BioResolve SCX mAb Consumables and Vanguard FIT Cartridges, go to: www.waters.com/bioresolve.
Waters, Empower, ACQUITY, Auto•Blend, UPLC, BioResolve and Vanguard are