Coupling of technologies delivers advanced information with superior speed and resolution compared to traditional Gel Permeation Chromatography (GPC)
The emergence of new and increasingly complex polymers with a broad range of structural and compositional diversity has been a driving force in the development of advanced analytical and separation technologies for polymer characterization. Today, analysts seek innovative techniques that allow them to better characterize and understand their highly complex samples. Combining high efficiency columns with the low overall system dispersion of Waters’ APC significantly improves resolution, especially for low molecular weight oligomers. In addition, run times can be up to 5X faster than with traditional Gel Permeation Chromatography (GPC), enabling higher sample throughput and more rapid method development.
Use of this high speed, high resolution separation technique has historically seen limited pairing with advanced online detectors, such as light scattering, due to limitations in the dispersion characteristics of these detectors. However, as the advantages of the APC become clearer, both in research and industry, manufacturers have been working to reduce dispersion within their advanced detector options, whilst maintaining the high resolution of the APC separation. Malvern Panalytical has achieved exactly this with its OMNISEC REVEAL multidetector module. Coupling the APC System to the OMNISEC REVEAL offers the ability to calculate absolute molecular weight, intrinsic viscosity and hydrodynamic radius. These parameters can be used to predict polymer behaviors in solutions/product matrices and to give a more comprehensive understanding of polymer structure. This speed of analysis and easy access to more detailed information provides a quicker pathway to the development of more successful and efficient products.
“Waters takes great pride in collaborating with innovative companies
like Malvern Panalytical to solve complex molecular characterization
challenges. This is an example of two leaders in our respective fields
working together to optimize the combination of our technologies in
order to help scientists achieve their analytical goals,” said
“Malvern Panalytical is proud to work with Waters to leverage the high
sensitivity and low dispersion characteristics of the OMNISEC REVEAL
advanced detector module, which are ideally suited to the APC system’s
high resolution and high efficiency separation characteristics. We
believe that researchers will be delighted with the analytical abilities
of the combined system, which offers extraordinary performance for the
analysis of both natural and synthetic polymers and provides visibility
of details that would otherwise be missed. The combination of Waters’
APC and Malvern Panalytical’s OMNISEC REVEAL opens new doors in polymer
research and development which will translate directly to better product
About Malvern Panalytical (www.malvern.com)
Malvern Panalytical technologies are used by scientists and engineers in a wide range of industries and organizations to solve the challenges associated with maximizing productivity, developing better quality products and getting them to market faster. Our mission is to create superior, customer-focused solutions and services to deliver tangible economic impact through chemical, physical and structural analysis of materials.
Underpinned by extensive industry knowledge and technical and applications expertise, Malvern Panalytical instruments help users better understand a wide variety of materials, from proteins and polymers to metals and building materials. Our technologies enable the measurement of parameters such as particle size, shape and zeta potential, biomolecular interactions and stability, rheological properties, elemental concentrations and crystallographic structure. Highly reliable and robust characterization of these properties is fundamental to predicting how a product will behave during use, to optimizing its performance and achieving manufacturing excellence.
Malvern Panalytical was formed by the merger of Malvern Instruments and
PANalytical on 1st
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Chris Orlando, 508-482-2623
Public Relations Manager
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