IVD LC-MS/MS System for Precise and Accurate Vitamin D Analysis
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Waters CE-Marks In Vitro Diagnostic MassTrak Vitamin D Solution (Photo: Business Wire)
“Our MassTrak Vitamin D Solution is the first, CE-marked, single-vendor
system to measure both vitamins 25(OH) D2 and D3 independently
and accurately from human plasma and serum in a single analysis,” said
Vitamin D, the main source of which is from dietary intake, is part of a family of fat-soluble secosteroids and has two major forms - ergocalciferol (plant derived Vitamin D2) and cholecalciferol (animal derived Vitamin D3). Vitamin D is also derived from the conversion of 7-dihydrocholesterol to Vitamin D3 following exposure of skin to sunlight. Increasingly, research is revealing the importance of vitamin D in protecting against a host of health problems. In the absence of vitamin D, bones can become brittle and thin. The research also suggests that vitamin D plays a role in modulating cell growth, the function of neuromuscular and immune systems, and reducing inflammation. It also indicates that those most at risk of a vitamin D deficiency are those who shun the sun, have milk allergies, adhere to a strict vegan diet, or suffer from certain diseases.
Due, in part, to mounting evidence of the importance of vitamin D to
human health and to news media coverage,
The MassTrak Vitamin D Solution is configured with the Waters ACQUITY
UPLC® I-Class/ Xevo®
TQD IVD System, the MassTrak Vitamin D Kit and MassLynx®
(IVD) Mass Spectrometry Software. The MassTrak Vitamin D Kit provides
metrological traceability to the
LC-MS/MS in the
In pursuit of better accuracy and precision for clinical laboratory analyses, liquid chromatography tandem mass spectrometry (LC-MS/MS) is rapidly becoming the analytical technique of choice. Waters IVD LC-MS/MS medical devices provide clinical laboratories access to technologies delivering selectivity, sensitivity and versatility – performance characteristics that traditional methods, such as immunoassays, often struggle to meet.
Designed to optimize workflow from pre-analytics to post-analytics, our system portfolio offers a wide variety of options for the routine use of LC-MS/MS in the clinical laboratory.
For more information: www.waters.com/vitamind
*For in vitro diagnostic use. Not available for sale in all countries.
1. Arch Pathol Lab Med. 2014 February ; 138(2): 189–203. doi:10.5858/arpa.2013-0149-OA
Waters, UPLC, ACQUITY, ACQUITY UPLC, Xevo, MassLynx and MassTrak are
Brian J. Murphy, +1 508-482-2614