Direct Sample Classification by Mass Spectrometry Speeds Creation of Test Results and Decision-Making
“Information on food samples separated in time and space from where it
is needed most isn’t efficient and hurts productivity. We’ve designed
LiveID Software to make the process of getting real-time information
about samples as intuitive, as quick and as easy as possible,” said
Ronan O’Malley, Senior Director of Informatics Products,
Food fraud - when food is labelled and sold as something that it is not - is a growing and pernicious problem that funds organized crime, cheats consumers and jeopardizes the reputation of food producers and the health of economies dependent on food exports.
In recent years, QTof mass spectrometry has emerged as a promising
technique for detecting food fraud. One who has pioneered its use for
this application is Professor
Faster than conventional techniques like immunosassay and PCR, mass spectrometry enabled by LiveID Software produces definitive results in seconds. With iKnife Sampling and REIMS, no sample pretreatment or separation is typically necessary. When the hand-held iKnife sampling device comes in contact with a sample of animal or plant tissue or other processed foodstuffs such as butter, it creates smoke containing compound-specific molecules which are directed to the REIMS source where the molecules are ionized and then passed on to be detected by the mass spectrometer. In very little time, the LiveID software then creates a molecular profile or chemical fingerprint of the sample, compares it to a user-generated database of reference fingerprints and then classifies the sample as belonging to one of a number of sample types or groupings.
Waters introduced iKnife Sampling and REIMS technologies to its QTof mass spectrometers in 2015. Since then, Waters has evolved the design of the REIMS source to make real-time decision-making using mass spectrometry straightforward and accessible by researchers who wish to explore the potential of the technology.
For more information on the Waters LiveID software, see www.waters.com/liveid.
Waters, Xevo, iKnife, REIMS, MassLynx, SYNAPT and LiveID are trademarks
Brian J. Murphy, +1 508-482-2614